Katie Perkins, who scored her 3000th List-A run for the HEARTS on Saturday, will again lead the side in Down’s absence.
Last week saw five List-A debutants in Anna Browning, Sydney Bultitude, Breearne Illing, Emma Irwin and Amberly Parr.
This week, Prue Catton and Josie Penfold await their turn, joining the 14-strong squad.
While the HEARTS get two final opportunities to showcase their skills and move up the Hallyburton Johnstone Shield table, Northern Districts can still push for a spot in the Grand Final.
Hallyburton Johnstone Shield | vs. Northern Districts